What is the role of recombinase in generating lymphocyte diversity?

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10-02-2017
Biology

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What is the role of recombinase in generating lymphocyte diversity?

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OfficialPyrocynical OfficialPyrocynical · Answer 1 · 2017-02-10T17:29:15+01:00

OfficialPyrocynical OfficialPyrocynical

10-02-2017

Allow deletion of DNA loops for recombination. Complementary sequences of RSS form H-bonds, RAG-1 and RAG-2 hold the pieces together, V(D)J recombinase cuts out loop of DNA, ends are ligated together with junctional and insertional flexibility.

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